Publications by authors named "K Shams"
Article Synopsis
- The study focused on elderly patients (70+) undergoing primary percutaneous coronary intervention (pPCI) for ST-elevation myocardial infarction (STEMI) at a tertiary center in Upper Egypt, highlighting a growing concern for cardiovascular disease in aging populations.
- The research included data from 3,627 patients, finding that 15.9% were elderly, with significantly higher in-hospital mortality rates, particularly among octogenarians (23.3%) compared to younger patients (4%).
- Elderly patients showed distinct clinical characteristics, such as higher rates of hypertension and chronic kidney disease, and were more likely to have severe complications post-procedure, emphasizing the need for tailored strategies in managing this demographic in cardiovascular care.
Late coronary complications after an arterial switch operation (ASO) may occur due to vessel kinking, compression resulting from growth of the great vessels, ostial fibro-intimal thickening after reimplantation or possibly secondary to accelerated atherosclerosis. Given that many of these patients are asymptomatic, adult ASO survivors require special attention and an individualised approach to the early detection of coronary artery disease. Most previously reported cases of coronary artery disease after an ASO have been managed surgically.
View Article and Find Full Text PDFADIPOPHILIN PEPTIDE (ADPH 129-137) IS NOT A TARGET ANTIGEN FOR CD8 T-CELLS IN PATIENTS WITH OBESITY.
Acta Endocrinol (Buchar)
October 2024
Context: In obesity, the infiltration of leukocytes into adipose tissue seems to play a key role in the development of inflammation and insulin resistance. Over-expression of adipophilin (ADPH) in adipose tissue, a protein which regulates lipid droplet structure and formation, has been reported in some studies.
Objective: To investigate the role of ADPH 129-137 as a target for CD8+ T-cells in PBMCs of patients with obesity.
Objective: The optimal management of pediatric type II supracondylar humerus fractures (SCHFs) is debated. We conducted a systematic review comparing outcomes and complications of nonoperative versus operative management to aid decision-making and inform future research.
Methods: We searched PubMed, Web of Science, MEDLINE, and CINAHL from their inception until February 7, 2024, including studies on pediatric patients (<18 y) with any type II SCHF, provided they compared operative to nonoperative care and were in English.