Publications by authors named "K Sevela"

Article Synopsis
  • A case study presented an elderly woman with systemic lambda-type AL amyloidosis, initially indicated by sudden high levels of beta-carotene and distinct skin changes.
  • Diagnosis involved skin biopsies revealing lambda light chain proteins along with co-deposited proteins, leading to initial confusion.
  • Ultimately, the patient died from renal failure related to amyloid nephropathy, with post-mortem examinations uncovering extensive amyloid deposits in various organs and unclear reasons for the high beta-carotene levels.
View Article and Find Full Text PDF

Contrast media-induced nephropathy (CMIN) is accompanied by high morbidity, lengthy hospitalization, and a higher mortality rate. In proportion to the rising number of diagnostic and interventional radiological procedures, the prevalence of this complication is also rising The study briefly tackles the currently known pathophysiological mechanisms that lead to CMIN and deals with various risk factors which increase the probability of development of contrast nephropathy. Among these factors are, in the first place, diabetes mellitus, a pre-existing renal illness and hypertension.

View Article and Find Full Text PDF

Contrast medium indicated nephropathy (CMIN) is a iatrogenic disorder by which patients become inflicted due to contrast medium exposure. Prevalence of this disorder might increase as more and more diagnostic and intervence radiology has been used. The article is focused on known pathofysiological mechanisms that are responsible for CMIN incidence.

View Article and Find Full Text PDF

In a retrospective study a total of 44 ambulatory examinations were made before enalapril was administered to 13 patients with essential hypertension and 52 ambulatory examinations during enalapril treatment of these patients. All patients were followed up on a long-term basis: 1. without enalapril treatment (2-24 months), 2.

View Article and Find Full Text PDF

Phthalic acid esters have been used for its softening and plastification effects as additives to various kinds of products: colours, paintings, glues, cosmetic products, inks, repellents, films, PVC-derived products including medical disposable PVC products. The authors present a basic review of literature on toxicologically important sources including medical disposable products. They refer about the deleterious effects on the mammalian organism, possibilities to replace phthalic acid esters by other softening and plasticizing remedies as well as the use of such kinds of materials, which do not require these additives.

View Article and Find Full Text PDF