Case Report: Major right-sided hepatectomies in infants in Uzbekistan: a case series.

Introduction: Liver resection is a critical surgical option for managing benign and malignant tumors, including rare and complex cases in pediatric patients. While such procedures are well-documented in adults, the surgical management of large liver neoplasms in infants poses unique challenges due to anatomical and physiological considerations, as well as the limited number of cases reported globally.

Aim: This study aimed to describe the initial experiences with major hepatectomies in infants with large liver neoplasms at our center.

Kaposi sarcoma of a liver graft in living donor liver transplantation: a rare case report.

Kaposi sarcoma following solid organ transplantation is a rare and underreported complication, with few cases documented globally concerning its origin from liver grafts. This case report describes an Asian woman who developed Kaposi sarcoma in a liver graft following living donor liver transplantation for end-stage liver disease resulting from hepatitis D virus. In accordance with current guidelines, standard immunosuppression was discontinued, and mammalian target of rapamycin (mTOR) inhibitors were initiated.

Evaluation and Management of Living Donors in the Setting of Living Donor Liver Transplant Program in the Republic of Uzbekistan.

In the Republic of Uzbekistan, the history of liver transplantation began in 2018, but this type of medical care was introduced regularly only in 2021. The selection, preparation, and perioperative management of living liver donors can be complicated and have importance in the type of responsible medical care, which requires maximum doctor involvement at all stages. This review has detailed the donor selection algorithm in the Republic of Uzbekistan, donor preparation for liver resection, and basic principles of liver resection surgery in living donors.

Liver Graft Machine Perfusion: From History Perspective to Modern Approaches in Transplant Surgery.

The shortage of donor organs remains an unresolved issue in livertransplantation worldwide. Consequently, strategies for expanding the donor pool are currently being developed. Donors meeting extended criteria undergo thorough evaluation, as livers obtained from marginal donors yield poorer outcomes in recipients, including exacerbated reperfusion injury, acute kidney injury, early graft dysfunction, and primary nonfunctioning graft.

Implementation of a living donor liver transplantation program in the Republic of Uzbekistan: a report of the first 40 cases.

Background: Living donor liver transplantation (LDLT) is an effective treatment for patients with end-stage liver disease. This study was performed to evaluate the outcomes of the initial series of LDLT procedures performed in the Republic of Uzbekistan and to demonstrate that liver transplantation is viable under the conditions in this country.

Methods: Between October 2021 and December 2023, we performed 40 LDLTs.