Publications by authors named "K Sekine"
Article Synopsis
- Non-triple helical collagen polypeptides (NTHs) are produced in tumor cells and tissues, lacking the typical collagen structure, and were found in various tumor cell lines and human lung cancer samples.
- NTH production is influenced by serum concentration and hypoxic conditions, and they may play a role in tumor angiogenesis despite the presence of adequate ascorbic acid.
- The study indicates that NTH production correlates with the accumulation of hypoxia-inducible factor-1α (HIF-1α), but HIF-1α doesn’t directly drive NTH α1(IV) production, suggesting NTHs could be potential therapeutic targets for cancer treatment.
Little is known about how blood free amino acids (FAAs) change in metabolic dysfunction-associated steatotic liver disease (MASLD). This study aims to identify the imbalance of FAAs in MASLD and explore its correction as a potential therapeutic target. We analyzed plasma FAAs data from 23,036 individuals with steatosis information from a biobank in Japan, and 310 patients with MASLD were enrolled.
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- This study focuses on how different designs of lingual brackets and wire materials affect the torque generated during orthodontic adjustments with third-order bends.
- Three types of self-ligation lingual brackets were tested: AL, CL, and ST, each with varying slot shapes and dimensions.
- Results showed that the AL-bracket produced the highest torque, while the CL-bracket had the least torque with square wires but more than ST with rectangular wires, indicating wire material and bracket shape play significant roles in treatment outcomes.
An 18-year-old male, diagnosed with urethritis and treated with minocycline for six days, presented to our hospital complaining of abdominal pain and nausea. Blood tests and contrast-enhanced computed tomography (CT) showed severe acute pancreatitis. Based on his medical history, blood tests, and imaging studies, common etiologies of acute pancreatitis were excluded, including alcohol intake, anatomical abnormalities of the pancreas and biliary tract, stones, malignancy, autoimmune diseases, and lipid abnormalities.
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