Approaches to prioritising research for clinical trial networks: a scoping review.

Background: Prioritisation of clinical trials ensures that the research conducted meets the needs of stakeholders, makes the best use of resources and avoids duplication. The aim of this review was to identify and critically appraise approaches to research prioritisation applicable to clinical trials, to inform best practice guidelines for clinical trial networks and funders.

Methods: A scoping review of English-language published literature and research organisation websites (January 2000 to January 2020) was undertaken to identify primary studies, approaches and criteria for research prioritisation.

[Psychosocial aspects of extremely tall girls with a treatment-induced precocious puberty (author's transl)].

Is psychosocial development influenced by tall stature and/or induced precocious puberty? This question was examined in 20 girls at 9,5 to 15,8 years of age who were admitted to estrogen treatment because of excessive constitutional tallness. Additionally, reference was made to the results of psychologically directed interviews with 86 girls who had undergone such treatment when 9 to 13 years old, and who belonged to a total collective of 387 tall girls cared for in the years 1966 to 1980. About half of the girls let discern symptoms pointing to neurosis, culminating in late puberty (age of dancing-lesion).

Psychic and intellectual development in girls with precocious puberty.

Examinations of psychic and intellectual development were made in 9 girls with idiopathic precocious puberty. The question was, whether precocious somatic maturation corresponds with an accelerated development of intellectual efficiency and psycho-social behaviour. Whereas psychodiagnostic investigations and questionnaires to parents and teachers suggested age-related, normal results, there was found a remarkable tendency to elevated IQ values, averaging 123.

[Group talk psychotherapy with adolescents (author's transl)].

The authors give a report about their experiences of five years on group talk psychotherapy with adolescents. The indication to take part in this method which is integrated in a multidimensional therapeutic concept, consists in psychosocial disturbances with crises. Mainly adolescents of 14-18 years of age are taken care of in the groups.