Induced chirality at the surface: fixation of a dynamic / invertible helical Co complex on SiO.

Dynamic / invertible helicity was successfully induced at a SiO surface immobilized with a dynamic helical trinuclear cobalt complex, [LCo(NHMe)](OTf), using chiral (() or ())-1-phenylethylamine. Solid-state CD spectra and theoretical calculations suggested that the fixation of the / helical complex on the surface coordination interactions was the key factor of the induced chirality at the surface.

Scleral Thickness in Central Serous Chorioretinopathy.

Purpose: To evaluate scleral thickness in central serous chorioretinopathy (CSC) using anterior segment (AS) OCT.

Design: Retrospective, comparative study.

Participants: Forty-seven eyes of 40 patients with CSC and 53 eyes of 47 age- and gender-matched normal control participants.

Mitotic cyclin Clb4 is required for the intracellular adaptation to glucose starvation in Saccharomyces cerevisiae.

Cellular homeostasis in response to glucose availability is maintained through the tight coordination of various physiological processes, including cell proliferation, transcription, and metabolism. In this study, we use the budding yeast Saccharomyces cerevisiae to identify proteins implicated in carbon source-dependent modulation of physiological processes. We find that the mitotic cyclin Clb4 is required for optimal regulation of glucose-starvation-responsive pathways through the target of rapamycin complex 1.

[Risk of Acute Kidney Injury in Patients Treated with Vancomycin and Piperacillin/Tazobactam Compared to Vancomycin and Meropenem or Doripenem: A Retrospective Cohort Study].

It has been reported that the risk of acute kidney injury (AKI) is higher during treatment with vancomycin and piperacillin/tazobactam compared to use of vancomycin and cefepim or meropenem. We investigated the risk of AKI in patients receiving vancomycin and piperacillin/tazobactam versus those receiving vancomycin and meropenem or doripenem. The subjects were patients over 18 years old who received either vancomycin and piperacillin/tazobactam (V+P/T therapy) or vancomycin and carbapenems (meropenem or doripenem) (V+C therapy) for at least 48 h between 1 May 2013 and 28 February 2019.

Chemoselective epoxidation of cholesterol derivatives on a surface-designed molecularly imprinted Ru-porphyrin catalyst.

A new molecularly imprinted Ru-porphyrin complex catalyst on a SiO2 support was designed, prepared, and characterized in a step-by-step manner for the C5[double bond, length as m-dash]C6 epoxidation of cholesterol derivatives. High chemoselectivity for the C5[double bond, length as m-dash]C6 epoxidation of cholesterol derivatives without protecting the 3-position OH group and other oxidizable functional groups was achieved on the molecularly imprinted catalyst.