The physiological performance of ectotherms is influenced by temperature, raising concerns about the impact of global warming on ectotherms. Understanding the relationship between ecologically relevant temperatures and the physiological performance of ectotherms provides a basis for assessing their resilience to changing environments. Absolute aerobic scope (AAS) is a functional metric of the thermal performance of aquatic ectotherms.
View Article and Find Full Text PDFThoracic descending aortic perforation with overlap syndrome (systemic sclerosis and dermatomyositis) is a rare, unreported vascular pathology. We describe the case of a 75-year-old woman who presented with chest tightness, back pain, and dyspnea. Computed tomography revealed a pinhole rupture in the descending aorta.
View Article and Find Full Text PDFPeripheral endothelial function, which accounts for the variability in shear stimulus, can be assessed using shear-mediated dilation normalized to the increased shear stimulus. Similarly, shear-mediated dilation of the internal carotid artery (ICA), an index of cerebrovascular endothelial function, should be normalized to increased shear stimulus. However, this approach has not yet been validated.
View Article and Find Full Text PDFPituitary adenylate cyclase-activating polypeptide (PACAP) affects rodents' stress-related behaviors, such as anxiety-like behavior or fear conditioning. However, previous studies have investigated the effect of intracerebroventricular, but not hippocampal, injection of this PAC1R-selective antagonist (PACAP-6-38) on anxiety-like behavior. However, it has been reported that administration of PACAP-6-38 to the dorsal hippocampus reduces the fear response in a fear conditioning test.
View Article and Find Full Text PDFCirc J
December 2024