Association between smartphone addiction and sedentary behaviour amongst children, adolescents and young adults: A Systematic Review and meta-analysis.

Background: The rapid proliferation of smartphones has raised concerns about their impact on physical activity levels, particularly among younger demographics. While smartphones offer numerous benefits, there is growing evidence to suggest that excessive use may lead to sedentary behaviours, potentially impacting physical health adversely. Hence, this review was done to explore the association between smartphone addiction and reduced physical activity amongst children, adolescents and young adults.

Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer.

Peritoneal carcinomatosis is a common yet deadly manifestation of gastrointestinal cancers, with few effective treatments. To identify targetable determinants of peritoneal metastasis, we focused on appendiceal adenocarcinoma (AC), a gastrointestinal cancer that metastasizes almost exclusively to the peritoneum. Current treatments are extrapolated from colorectal cancer (CRC), yet AC has distinct genomic alterations, mucinous morphology and peritoneum restricted metastatic pattern.

Stress management with HRV following AI, semantic ontology, genetic algorithm and tree explainer.

Heart Rate Variability (HRV) serves as a vital marker of stress levels, with lower HRV indicating higher stress. It measures the variation in the time between heartbeats and offers insights into health. Artificial intelligence (AI) research aims to use HRV data for accurate stress level classification, aiding early detection and well-being approaches.

Role of Cellular Mechanisms in Dengue Pathogenesis: Focus on Immune Cells Interactions.

Dengue is an arbovirus mosquito-borne disease that occurs after an infection with dengue virus. Dengue virus releases E-proteins, which act as binding proteins and enter the host cell after infection. It triggers several cellular reactions and activates the immune system; however, the mechanisms are still poorly understood.

Peripheral dose assessment in radiation therapy using photon beams: experimental results with optically stimulated luminescence dosimeter.

The estimation of peripheral dose (PD) is vital in cancer patients with long life expectancy. Assessment of PD to radiosensitive organs is important to determine the possible risk of late effects. An attempt has been made to assess the peripheral dose using optically stimulated luminescence dosimeter (OSLD) with megavoltage photon beams as a function of field size, depth, energy, and distance from the field edge.