Identification and stability analysis of potential ADP-ribose modification sites on vascular endothelial growth factor (VEGF) through molecular dynamics simulation.

Post-translational modifications (PTMs) are crucial covalent processes that alter protein properties, achieved through proteolytic cleavage or addition of modifying groups like acetyl, phosphoryl, glycosyl, or methyl to amino acids. ADP-ribosylation is a reversible post-translational modification, where ADP-ribose units are covalently attached to target protein side chains. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that plays a key role in physiological and pathological conditions.

Kangaroo mother care utilization at stepdown ward of a tertiary care teaching hospital: a quality improvement study.

Purpose: India has the highest burden of preterm/low birth weight newborns. To tackle this, Kangaroo Mother Care (KMC) needs to be scaled up. We did a quality improvement (QI) study to increase KMC coverage to 80% and its utilization to at least 4 h/infant/day.

Tapping private health sector for public health program? Findings of a novel intervention to tackle TB in Mumbai, India.

Background: India carries one-fourth of the global tuberculosis (TB) burden. Hence the country has drafted the ambitious National Strategic Plan to eliminate tuberculosis by 2025. To realise this goal, India's Revised National Tuberculosis Control Programme (RNTCP) and partners piloted a novel strategy to engage private-providers for tuberculosis care via a "Private-provider Interface Agency" (PPIA) in Mumbai and other locations.

Comparative Evaluation of the Strength of Denture Base Resin repaired with Glass Fiber-reinforced Acrylic Resin: An in vitro Study.

Aim: The present study aimed at evaluating and comparing the transverse strength of heat polymerizing acrylic resin samples repaired using glass fiber-reinforced autopolymerizing acrylic resin with varying gap widths at the fracture site.

Materials And Methods: Heat polymerizing acrylic resin samples of dimensions 65 * 10 * 2.5 mm each were fabricated.