Production of biologically active recombinant salmon calcitonin in Escherichia coli and fish cell line.

Salmon calcitonin is a small peptide hormone synthesised and released by a specialised gland called ultimobranchial gland in fish. This hormone has been used to treat osteoporosis for over 50 years. The aim of this study was to compare the efficacy of five repeats of salmon calcitonin (5sCT) produced in two different hosts (bacteria and fish cell line).

Exploring Acupuncture as an Adjunctive Therapy for Puberty Menorrhagia: A Case Report.

Background: Puberty menorrhagia, characterized by prolonged and excessive menstrual bleeding between menarche and 19 years of age, presents clinical challenges at adolescents and it is attributed to an immature hypothalamo-pituitary-ovarian axis, leading to sustained high estrogen levels and anovulation. This case report explores the efficacy of acupuncture as an adjunctive therapy for pubertal menorrhagia of a 16-year-old female with a history of irregular menstrual cycles and excessive bleeding for 41 days.

Methodology: Based on Traditional Chinese Medicine (TCM) tongue and pulse diagnostics of the patient, acupuncture needling at SP4 (Gongsun), PC 6 (Neiguan), KI 14 (Siman), SP 10 (Xuehai), LR 1 (Dadun), CV 6 (Qihai) was given once in a day for a month, each session lasting 20 min targeting to alleviate Liver blood stasis.

Investigating the Anticancer Potential of Biochanin A in KB Oral Cancer Cells Through the NFκB Pathway.

Squamous cell carcinoma (SCC) is a malignancy primarily affecting squamous cells. Its development is linked to multiple risk factors, such as alcohol and tobacco consumption, human papillomavirus (HPV) infection, and Epstein-Barr Virus (EBV) infection. Biochanin A (BCA), a phytoestrogen extracted from red clover, has been extensively researched for its therapeutic properties.

Development and characterization of brain cell line from Trachinotus blochii and its application in virological and gene expression studies.

A permanent cell line, SPB (Snubnose pompano brain) was established from Trachinotus blochii by the explant culture method. It has been sub-cultured more than 75 passages and showed optimal growth at 28°C using L-15 medium supplemented with 15% to 20% FBS. The SPB cells were cryopreserved at different passage levels for various applications.

ExpHBA Deep-IoT: Exponential Honey Badger Optimized Deep Learning For Breast Cancer Detection in IoT Healthcare System.

Breast cancer (BC) is the most widely found disease among women in the world. The early detection of BC can frequently lessen the mortality rate as well as progress the probability of providing proper treatment. Hence, this paper focuses on devising the Exponential Honey Badger Optimization-based Deep Covolutional Neural Network (EHBO-based DCNN) for early identification of BC in the Internet of Things (IoT).