Direct and chemoselective transformation of cysteine to dehydroalanine on peptides.

A direct method for the preparation of peptides containing a dehydroalanine residue was developed through the chemoselective transformation of a cysteine residue in peptides, under the influence of cesium carbonate.

Association between changes in walking time and all-cause mortality among survivors of the Great East Japan Earthquake: the Research Project for Prospective Investigation of Health Problems Among Survivors of the Great East Japan Earthquake and Tsunami Disaster (RIAS) study.

Introduction: Several studies have investigated the association between physical activity (PA) and all-cause mortality. However, no study has systematically examined the association between PA changes and all-cause mortality among residents of disaster-stricken areas. This study aimed to clarify the association between PA changes and the risk of all-cause mortality among survivors of the Great East Japan Earthquake.

Comment on Pu et al. Predicting Postoperative Lung Cancer Recurrence and Survival Using Cox Proportional Hazards Regression and Machine Learning. 2025, , 33.

Pu et al [...

Cumulative impact of procedural and anatomical factors on in-hospital bleeding complications in endovascular therapy for lower-extremity artery disease: A nationwide registry study in Japan.

Although bleeding is a common procedure-related adverse event following endovascular therapy (EVT), limited data exist regarding the procedural and anatomical factors associated with its complications in patients with lower-extremity artery disease (LEAD) undergoing EVT. Data were extracted from a nationwide Japanese EVT registry of 73,990 patients who underwent EVT for symptomatic LEAD between January 2021 and December 2022. The primary outcome measure was in-hospital bleeding complications, including access site bleeding, nonaccess site bleeding, and hemorrhagic stroke.

Validity of a qualitative visual method for diagnosing forward head posture.

Introduction: Forward head posture (FHP) is quantitatively diagnosed by measuring the craniovertebral angle (CVA). A qualitative visual method has recently been introduced but the validity of this method has not been confirmed. The present study aimed to clarify the validity of the visual method, using CVA methods as a standard.