Publications by authors named "K Saiki"

Prediabetes disproportionately affects racial and ethnic minority groups in Hawai'i. The National Diabetes Prevention Program lifestyle change program (National DPP LCP) decreases the risk of developing diabetes. However, enrolling and retaining participants is a challenge for program providers.

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Background: Robot-assisted surgery is widely performed for renal cell carcinoma (RCC) with inferior vena cava (IVC) tumor thrombi. Although many chemotherapeutic options are available for the treatment of unresectable RCC, there are very few reports on robot-assisted radical nephrectomy (RARN) with inferior vena cava thrombectomy (IVCT) after presurgical treatment with immune checkpoint inhibitors and tyrosine kinase inhibitors. We believe that pre-surgical treatment can provide minimally invasive surgical benefits to high-risk patients during the perioperative period.

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Osteoporosis in postmenopausal women is one of the causes of femoral fractures and is prevented by the administration of bisphosphonates. Individual morphologies are considered to increase the risk of atypical fractures associated with long-term administration. To evaluate cortical bone morphology quantitatively, we established a method to measure the distance from the center point of a cross-section to the external and internal borders based on CT images.

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Article Synopsis
  • The Briganti nomogram, with a 5% cut-off, is used to decide if pelvic lymph node dissection (PLND) is necessary for prostate cancer patients.
  • A study analyzed data from 1,068 patients who had radical prostatectomy and found no significant oncological benefit of PLND for those with a Briganti score of 5%.
  • High PSA levels and advanced T-stage were linked to worse biochemical recurrence-free survival, while PLND did not have a meaningful impact on recurrence outcomes.
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Article Synopsis
  • A 75-year-old man experienced blurred vision and nasal bleeding, leading to a diagnosis of hyperviscosity syndrome and central retinal vein occlusion due to Waldenström macroglobulinemia.
  • Immediate plasma-exchange treatment was initiated to reduce blood viscosity, initially planned with a saline predilution method, but it was adjusted as the treatment volume was manageable without increasing total membrane pressure.
  • After two days of plasma exchange and subsequent chemotherapy, the patient's IgM levels dropped significantly, his visual symptoms improved, and he was discharged, suggesting that initial plasma exchange strategies can be tailored for safety and effectiveness.
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