Publications by authors named "K Sagoe"
Between October 2021 and February 2022, there was an outbreak of Yellow fever that spread within several districts in the northern part of Ghana. Febrile illnesses such as Yellow fever are often misdiagnosed as malaria and vice versa, which delays appropriate management and treatment. Hence, the true burden of Yellow fever and malaria are mostly underestimated.
View Article and Find Full Text PDFIntroduction: Foodborne infections are caused by a wide spectrum of microbial pathogens, and they pose a significant global health threat, resulting in millions of cases and thousands of fatalities annually. Among these pathogens, human viruses, including Hepatitis A virus (HAV) and Hepatitis E virus (HEV), play a significant role in foodborne viral outbreaks, especially in Africa. This systematic review determined the prevalence of these viruses in livestock and produce in Africa.
View Article and Find Full Text PDFObjective: Routine viral load and drug resistance testing are well supported in most resource-rich settings and provide valuable benefits in the clinical care of PLWH in these communities. Undoubtedly, there exist financial and political constraints for the scale-up of viral load and drug resistance testing in Sub-Saharan Africa. To achieve the global UNAIDS 95/95/95 targets, there is the need to bridge this inequity in patient care and allow for a universal approach that leaves no community behind.
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- - The study compared Sanger sequencing and next-generation sequencing (NGS) to detect drug-resistance mutations in HIV-1 among treatment-naive patients in Ghana, aiming to find minority mutations that could lead to treatment failure.
- - NGS identified 25 mutations in the HIV genes compared to 21 by Sanger sequencing, revealing a higher detection rate of minority drug resistance mutations (55% vs. 35%).
- - Results suggest NGS is more effective for accurate drug resistance testing and highlight the need for its implementation in clinical settings in Ghana, as Sanger sequencing alone may miss significant mutations.
Background: Malaria is a common and severe public health problem in Ghana and largely responsible for febrile symptoms presented at health facilities in the country. Other infectious diseases, including COVID-19, may mimic malaria due to their shared non-specific symptoms such as fever and headache thus leading to misdiagnosis. This study therefore investigated COVID-19 among patients presenting with malaria-like symptoms at Korle-Bu Polyclinic, Accra, Ghana.
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