Publications by authors named "K S Wisdom"

Article Synopsis
  • Tumors that do not respond to immunotherapy create barriers that hinder T-cell effectiveness, so improving T-cell movement into these tumors could enhance treatment success.
  • Advanced in-vitro models can mimic the complex conditions of tumors, making research findings more applicable to real patient scenarios.
  • The study introduced a new scalable microfluidic assay that allows researchers to examine T-cell movement and function in 3D tumor environments, providing insights crucial for developing better cancer immunotherapy strategies.
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Lung cancer is a leading cause of death worldwide, with only a fraction of patients responding to immunotherapy. The correlation between increased T-cell infiltration and positive patient outcomes has motivated the search for therapeutics promoting T-cell infiltration. While transwell and spheroid platforms have been employed, these models lack flow and endothelial barriers, and cannot faithfully model T-cell adhesion, extravasation, and migration through 3D tissue.

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We examined whether pairing pregnant women with community health workers improved pregnancy outcomes among 254 Black women with singleton pregnancies participating in the Women-Inspired Neighborhood (WIN) Network: Detroit using a case-control design. A subset (N = 63) of women were recontacted and asked about program satisfaction, opportunities, and health behaviors. Michigan Vital Statistics records were used to ascertain controls (N = 12,030) and pregnancy and infant health outcomes.

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This quantitative study aimed to better understand how teachers implement technology in a variety of teaching modalities to enhance content delivery and student engagement. More specifically, it aimed to investigate the digital divide of technology usage based upon school setting and usage frequency. Responses were collected using a random sampling method of full-time K-12 public school teachers in a Mid-Atlantic state.

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In the present work the nonapeptides i.e., isotocin and vasotocin alone or in a combination were tested in to evaluate their effect on stripping by abdominal massage.

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