Proteomics-based aging clocks in midlife and late-life and risk of dementia.

Biological age can be quantified by composite proteomic scores, called aging clocks. We investigated whether biological age acceleration (a discrepancy between chronological and biological age) in midlife and late-life is associated with cognitive function and risk of dementia. We used two population-based cohort studies: Atherosclerosis Risk in Communities (ARIC) Study and Multi-Ethnic Study of Atherosclerosis (MESA).

Corrigendum: Case Report: A rare presentation of rapidly progressive moyamoya disease refractory to unilateral surgical revascularization.

[This corrects the article DOI: 10.3389/fsurg.2024.

Finding My Way: Black Doulas' Communication with Other Birthing Care Providers in an Interprofessional Work Environment.

Black women suffer more complications and birthing harms compared to other race-ethnic groups. Even when birthing equity initiatives are implemented, many Black families choose to work with a Black doula to reduce harms linked to obstetric racism. Most Black doulas described their role as helping women have the kind of birth they want; however, problems doulas experience in communicating with other birthing team members are not well understood.

Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance.

Microbial species must compete for space and nutrients to persist in the gastrointestinal (GI) tract, and our understanding of the complex pathobiont-microbiota interactions is far from complete. Klebsiella pneumoniae, a problematic, often drug-resistant nosocomial pathogen, can colonize the GI tract asymptomatically, serving as an infection reservoir. To provide insight on how K.

First Measurement: Proactive Immune Cell Sparing in Radiation Therapy.

Purpose: Radiation Therapy (RT) can modulate the immune system and generate anti-tumor T cells. However, this anti-tumor-activity is countered by radiation-induced immunosuppression (RIIS). Clinical advantages of proactively sparing RT dose to immune rich organs have not previously been evaluated.