Dexmedetomidine for analgesia and sedation for procedural pain or discomfort in newborn infants.

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of dexmedetomidine compared with opioids, non-opioids and placebo in providing sedation and analgesia for procedural pain in newborn infants.

More than meets the eye: predicting adrenocortical carcinoma outcomes with pathomics.

Background: Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with high recurrence rates and poor prognosis. Current prognostic models are inadequate, highlighting the need for innovative diagnostic tools. Pathomics, which utilizes computer algorithms to analyze whole-slide images, offers a promising approach to enhance prognostic models for ACC.

The Impact of COVID-19 Pandemic on the Diagnosis, Treatment, and Outcomes of Colorectal Cancer in Singapore.

: During the COVID-19 pandemic, many countries implemented lockdowns and social distancing measures, which may delay the early diagnosis of colorectal cancer (CRC). This study aims to review the impact of the pandemic on the diagnosis and treatment outcomes of CRC. : Patients who underwent colonoscopy or surgery for CRC were included.

Hydrate-Based Methane Storage in Biodegradable Hydrogels Absorbing Dilute Sodium P-Styrenesulfonate Solution.

Developing an exceptional reaction medium with high promotion efficiency, desirable biodegradability and good recyclability is necessary for hydrate-based methane storage. In this work, a kind of eco-friendly hydrogel, polyvinyl alcohol-co-acrylic acid (PVA-co-PAA), was utilized to absorb dilute sodium p-styrenesulfonate (SS) solution, for constructing a hybrid reaction medium for methane hydrate formation. Hydrogels or dilute SS solutions (1-4 mmol L) had weak or even no promoting effects on hydrate formation kinetics, while the combination of them could synergistically promote methane hydrate formation.

Coexistence of immunoglobulin G4-related kidney disease and acute hematogenous disseminated pulmonary tuberculosis: a case report.

Background: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibrous inflammatory disease. Recently, an association between IgG4-RD and tuberculosis (TB) has been reported.

Case Summary: We report a 56-year-old man complaining of a cough and poor appetite for 2 months and oliguria for 1 day.