Publications by authors named "K S Vishnyakova"

Article Synopsis
  • The Black Sea, a semi-enclosed inland sea, features anoxic deep waters and is home to various marine mammals, including local subspecies of dolphins and harbour porpoises.
  • Research teams from Bulgaria, Georgia, Romania, Türkiye, and Ukraine deployed F-PODs between September 2020 and October 2022 to study the acoustic activity of harbour porpoises, uncovering strong seasonal and diel patterns across different regions.
  • Findings indicated that porpoises in the southeastern Black Sea showed increased acoustic activity during the spring, aligning with the seasonal migration of anchovies, while western and northwestern porpoises demonstrated distinct bimodal and daylight activity patterns linked to the feeding habits of sprat.
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Marine and freshwater mammalian predators and fish samples, retrieved from environmental specimen banks (ESBs), natural history museum (NHMs) and other scientific collections, were analysed by LIFE APEX partners for a wide range of legacy and emerging contaminants (2545 in total). Network analysis was used to visualize the chemical occurrence data and reveal the predominant chemical mixtures for the freshwater and marine environments. For this purpose, a web tool was created to explore these chemical mixtures in predator-prey pairs.

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Clear cell renal cell carcinoma (ccRCC) accounts for 80-90% of kidney cancers worldwide. Small C-terminal domain phosphatases CTDSP1, CTDSP2, and CTDSPL (also known as SCP1, 2, 3) are involved in the regulation of several important pathways associated with carcinogenesis. In various cancer types, these phosphatases may demonstrate either antitumor or oncogenic activity.

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The toxic effects of four cationic porphyrins on various human cells were studied in vitro. It was found that, under dark conditions, porphyrins are almost nontoxic, while, under the action of light, the toxic effect was observed starting from nanomolar concentrations. At a concentration of 100 nM, porphyrins caused inhibition of metabolism in the MTT test in normal and cancer cells.

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It is known that the development of foci of chronic inflammation usually accompanies body aging. In these foci, senescent cells appear with a pro-inflammatory phenotype that helps maintain inflammation. Their removal with the help of senolytics significantly improves the general condition of the body and, according to many indicators, contributes to rejuvenation.

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