Biofiltration for odor mitigation in water resource recovery facilities.

Odor emissions, primarily from anthropogenic activities like waste treatment and industrial processes, pose significant challenges in urban areas, particularly near water resource recovery facilities. While these emissions are generally not toxic, they can adversely affect community wellbeing and investment, prompting stricter regulations in some regions. For example, New York State's hydrogen sulfide guidelines are more stringent than federal standards.

Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ: A Phase 1 Nonrandomized Clinical Trial.

Importance: Intratumoral immunotherapy that leverages the biological characteristics of high-risk ductal carcinoma in situ (DCIS) may be able to reduce the extent of surgical treatment and provide an alternative approach to improve patient outcomes.

Objective: To determine if combination intratumoral immunotherapy can activate immune cells to shrink or eliminate high-risk DCIS.

Design, Setting, And Participants: This phase 1 open-label nonrandomized clinical trial at a single academic center tested the safety and efficacy of intratumoral immunotherapy in patients with high-risk DCIS, defined as at least 2 of the following present: younger than 45 years, tumor size greater than 5 cm, high-grade, palpable mass, hormone receptor (HR)-negative, or ERBB2-positive.

Soil quality assessment in agricultural lands of an industrializing region of India.

Soil degradation due to industrialization is a growing global concern, emphasizing the importance of evaluating soil quality near industrial zones to ensure food security, environmental sustainability, and public health. This study compares soil quality across five industrial sites, including foundries, electroplating, paper mills, textile mills, and quarries and cement industries, in the Coimbatore district. Soil samples were collected via a purposive sampling approach from nearby agricultural fields via a 500 m grid.

Comprehensive study of Biginelli's compounds show antibacterial activity against Vibrio parahaemolyticus of two strains: In vitro and computational approaches.

This study addresses the critical challenges faced by global aquatic industries such as overfishing, habitat destruction, pollution, climate change, and unsustainable aquaculture practices. It focuses on developing effective solutions by synthesizing potent inhibitors against Vibrio parahaemolyticus of two strains namely: MTCC-451 (A) and Vp-S14 (B). Biginelli's compounds (B1-4) were identified as promising inhibitors with confirmed antibacterial activity through in silico and in vitro studies.