Publications by authors named "K S Pope"

Objective: We assessed the diagnostic performance of ultrasound two-dimensional shear wave elastography (US 2D-SWE) to predict clinically significant fibrosis (CSF) in patients with serologic iron overload (SIO) and the subgroup with histologic liver iron overload (LIO).

Methods: A single-center retrospective cross-sectional study of adults with SIO (serum ferritin ≥ 200 ng/mL in females and ≥ 300 ng/mL in males) and suspected chronic liver disease with nonfocal liver biopsy results and US 2D-SWE exams within 1 year was performed. Histopathological fibrosis stage ≥2 and liver iron ≥2+ was considered CSF and LIO, respectively.

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This paper presents research on the recreational impacts of harmful algal blooms (HABs) and other water quality changes in the U.S. heartland.

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Article Synopsis
  • The study aimed to assess the use of various palliative radiation therapy techniques across Australia and New Zealand, focusing on the preferences of radiation oncology practitioners.
  • An anonymous online survey was conducted with 146 radiation oncology fellows, revealing that many prefer advanced techniques like stereotactic body radiation therapy for specific cancer cases, though there is considerable variation in practice between Australia and New Zealand.
  • Results showed that New Zealand practitioners are more likely to use basic technologies due to limitations in the availability of advanced options and waiting lists, which impacts patient treatment choices.
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Malformations of the brain are common and vary in severity, from negligible to potentially fatal. Their causes have not been fully elucidated. Here, we report pathogenic variants in the core protein-folding machinery TRiC/CCT in individuals with brain malformations, intellectual disability, and seizures.

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