Publications by authors named "K S Nehal"
Melanoma of the lentigo maligna (LM) type is most commonly located on the head and neck region. This subtype of melanoma poses surgical challenges due to its location on anatomically sensitive areas and frequent presence of subclinical extension. To analyze the reconstruction patterns of LM patients undergoing margin-controlled surgery.
View Article and Find Full Text PDFMelanoma of the lentigo maligna (LM) type and its invasive counterpart, lentigo maligna melanoma (LMM), occur in chronically sun-damaged skin and tend to have subclinical extension that makes presurgical margin mapping challenging. Reflectance confocal microscopy (RCM) is a non-invasive imaging modality that enables in vivo visualization of the skin at the cellular level, allowing for adequate estimation of LM/LMM margins. We aimed to perform a systematic review and meta-analysis evaluating RCM's performance compared with histopathology in margin mapping of LM/LMM.
View Article and Find Full Text PDFArticle Synopsis
- - PDEMA, previously known as CCPDMA, allows for complete histologic visualization of tumor margins, which helps in accurately removing cancerous tissue while preserving healthy tissue.
- - It is the preferred treatment method by NCCN for certain skin cancers due to its high cure rates, with Mohs micrographic surgery being the most common PDEMA technique used in the U.S.
- - The article discusses the differences between Mohs and Tubingen PDEMA techniques, emphasizing the importance of collaboration between surgeons and pathologists, and includes a step-by-step Tubingen protocol with visual aids.
Background: In outbreak-prone settings, community-based surveillance (CBS) systems can alert health authorities to respond in a timely manner where suspected cases of disease are being reported. After the 2014-2016 Ebola outbreak, the WHO and other stakeholders supported the establishment of CBS in Sierra Leone, for which community health workers (CHW) were trained to collect and report symptoms data of 11 priority health conditions in their communities. Our study objective was to assess feasibility and challenges to sustain CBS in a low resource setting as part of a World Bank evaluation of Sierra Leone's Ministry of Health and Sanitation's (MoHS) CBS and electronic Integrated Disease Surveillance & Response (eIDSR) systems.
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- The study focuses on establishing Minimal Important Difference (MID) estimates for the FACE-Q Skin Cancer Module, a tool to measure patient outcomes after facial skin cancer surgery.
- Conducted at four U.S. hospitals from April 2020 to April 2022, 990 patients undergoing Mohs Micrographic Surgery provided data through various scales assessing satisfaction and distress at multiple time points.
- The findings indicated specific MID estimates for the scales, which are key for improving the understanding and application of patient-reported outcomes in clinical settings.