Publications by authors named "K S N Barroso"

Article Synopsis
  • The accumulation of improperly folded proteins in the endoplasmic reticulum causes ER stress, which triggers the unfolded protein response (UPR) that tumor cells, like those in glioblastoma (GB), exploit to enhance their growth and malignancy.
  • IRE1 alpha, a key player in the UPR, has been shown to promote GB invasion and immune cell infiltration, leading to poorer patient outcomes.
  • Research revealed that IRE1 signaling activates the UBE2D3 enzyme, which in turn stimulates the NFκB pathway to produce chemokines, facilitating myeloid cell infiltration in tumors and highlighting a new target for immunotherapy in GB.
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This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records.

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In this study, zinc and copper oxide nanoparticles (NPs) were synthesized using hemp (Cannabis sativa L.) leaves (ZnONP-HL and CuONP-HL), and their antifungal potential was assessed against Fusarium virguliforme in soybean (Glycine max L.).

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Nanoscale materials are promising tools for managing plant diseases and are becoming important players in the current agritech revolution. However, adopting modern methodologies requires a broad understanding of their effectiveness in solving target problems and their effects on the environment and food chain. Furthermore, it is paramount that such technologies are mechanistically and economically feasible for growers to adopt in order to be sustainable in the long run.

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