[The formation of the urine proteome in healthy human].

In the review it was represented the modern ideas on the processes involved in the formation of the protein composition of the urine of healthy people. In the last decade the development of highly sensitive mass spectrometric methods for the detection of proteins has given impetus to the study of the protein composition of human body fluids, including urine. Modern methods of separation of complex protein mixtures and determination of the individual components of these mixtures that are used in proteomics, can detect in urine significant number of proteins and peptides of different origin.