Publications by authors named "K S Krishnamoorthy"

A 10-year-old girl underwent successful device closure of a 15-mm atrial septal defect with a short and thick retroaortic rim using a 16-mm atrial septal occluder from the conventional approach under transesophageal echocardiographic guidance. There were no periprocedural complications. The aortic valve was noted to be trileaflet and competent.

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Article Synopsis
  • The study evaluated the performance of the Q Filariasis Antigen Test (QFAT) method versus the WHO-recommended Filariasis Test Strip (FTS) for detecting Wuchereria bancrofti in Karnataka, India, as part of the Global Programme to Eliminate Lymphatic Filariasis (GPELF).
  • A total of 1227 individuals aged 20 and older were tested with both methods during an epidemiological survey, and the results showed that QFAT detected 299 positives while FTS found 310 positives.
  • QFAT demonstrated high sensitivity (95.5%) and specificity (99.7%), and the results were nearly perfectly aligned with FTS, indicated by a strong Cohen
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A 3-month-old baby girl presenting with heart failure was found to have a large persistent ductus arteriosus as well as a bicuspid aortic valve with severe aortic stenosis. She underwent surgical ductal closure following which there was complete resolution of aortic valve gradients without requiring any aortic valve intervention. This case highlights the importance of understanding hemodynamics in efficacious management of congenital heart disease.

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Problems of finding confidence intervals (CIs) and prediction intervals (PIs) for two-parameter negative binomial distributions are considered. Simple CIs for the mean of a two-parameter negative binomial distribution based on some large sample methods are proposed and compared with the likelihood CIs. Proposed CIs are not only simple to compute, but also better than the likelihood CIs for moderate sample sizes.

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