Objective: Microwave lung ablation (MWA) is a minimally invasive and inexpensive alternative cancer treatment for patients who are not candidates for surgery/radiotherapy. However, a major challenge for MWA is its relatively high tumor recurrence rates, due to incomplete treatment as a result of inaccurate planning. We introduce a patient-specific, deep-learning model to accurately predict post-treatment ablation zones to aid planning and enable effective treatments.
View Article and Find Full Text PDFWomen with high mammographic density have an increased risk of breast cancer. They may be offered contrast-enhanced mammography to improve breast cancer screening performance. Using a cohort of women receiving contrast-enhanced mammography, we evaluated whether conventional and modified mammographic density measures were associated with breast cancer.
View Article and Find Full Text PDFThe liver is a common site for the development of metastases in colorectal cancer. Treatment selection for patients with colorectal liver metastases (CRLM) is difficult; although hepatic resection will cure a minority of CRLM patients, recurrence is common. Reliable preoperative prediction of recurrence could therefore be a valuable tool for physicians in selecting the best candidates for hepatic resection in the treatment of CRLM.
View Article and Find Full Text PDFPurpose: To evaluate a transmission optical spectroscopy instrument for rapid ex vivo assessment of core needle cancer biopsies (CNBs) at the point of care.
Materials And Methods: CNBs from surgically resected renal tumors and nontumor regions were scanned on their sampling trays with a custom spectroscopy instrument. After extracting principal spectral components, machine learning was used to train logistic regression, support vector machines, and random decision forest (RF) classifiers on 80% of randomized and stratified data.
Strong nonlinear absorption (NLA), reduced optical limiting (OL) thresholds, and high radiation shielding parameters are required for the effective use of glasses in the laser radiation and nuclear radiation protecting materials. In view of this, the efficacy of SmO on the nonlinear optical (NLO) and OL properties were ascertained (at 532 nm) along with radiation shielding characteristics. The open and closed aperture Z-scan profiles revealed the presence of positive NLA and nonlinear refraction (NLR) phenomena respectively.
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