Assessing COVID-19 outcomes among healthcare workers: a retrospective study.

Introduction: The purpose of this research was to investigate the outcomes of coronavirus disease 2019 (COVID-19) infection in healthcare workers, assess the incidence of infection among them, and identify factors linked to the severity of the disease.

Methodology: This cross-sectional study was conducted retrospectively in Duhok city, Kurdistan Region of Iraq, from September 2021 to January 2023.

Results: The study included 1,958 participants, of whom 1,338 (68.

Recent progress in nanoparticulate-based intranasal delivery for treating of different central nervous system diseases.

Drug administration to the central nervous system (CNS) has become a great obstacle because of several biological barriers, such as the blood-brain barrier, therefore, brain targeting insights are a light for scientists to move forward for treating neurogenerative diseases using advanced non-invasive methods. The current demand is to use a potential direct route as the nasal administration to transport drugs into the brain enhancing the BBB permeability and hence, increasing the bioavailability. Interestingly, recent techniques have been implanted in formulating nanocarriers-based therapeutics for targeting and treating ischemic stroke using lipid or polymeric-based materials.

Impact of real-time weather conditions on crash injury severity in Kentucky using the correlated random parameters logit model with heterogeneity in means.

The present study investigated the impact of real-time weather (air temperature, relative humidity, precipitation, wind speed, and solar radiation) on crash injury severity. Recent crash data (January 2016 to April 2021) on Interstate-75 in the state of Kentucky were merged with real-time weather information (retrieved from Kentucky Mesonet stations) at the 1-hour level. The severity index "SI" (i.

Cloning and periplasmic soluble expression of hepatitis B surface antigen gene in Escherichia coli.

Objective: The objective of this study was to clone and express the hepatitis B surface antigen gene (HBsAg) in Escherichia coli (E. coli), thereby aiming to develop potential local therapeutics for combating Hepatitis B virus (HBV) infection in the Pakistani community by producing HBsAg in E. coli.