Factors Impacting Discharge Destination Following Head and Neck Microvascular Reconstruction.

Objective: Determine which variables impact postoperative discharge destination following head and neck microvascular free flap reconstruction.

Study Design: Retrospective review of prospectively collected databases.

Methods: Consecutive patients undergoing head and neck microvascular free flap reconstruction between January 2010 and December 2019 (n = 1972) were included.

Rate versus rhythm control for atrial fibrillation: from AFFIRM to EAST-AFNET 4 - a paradigm shift.

The clinical choice between rate or rhythm control therapies has been debated over the years. In 2002, the AFFIRM trial demonstrated that the rhythm-control strategy had no survival advantage over the rate-control strategy. Eighteen years later, EAST-AFNET 4 showed that the rhythm-control approach is better than rate control in reducing adverse cardiovascular outcomes in patients with a recent diagnosis of atrial fibrillation (AF).

Effects of muscle damage on phosphorus magnetic resonance spectroscopy indices of energetic status and sarcolemma integrity in young mdx mice.

Phosphorus magnetic resonance spectroscopy ( P-MRS) has been shown to detect altered energetic status (e.g. the ratio of inorganic phosphate to phosphocreatine: Pi/PCr), intracellular acid-base status, and free intracellular magnesium ([Mg ]) in dystrophic muscle compared with unaffected muscle; however, the causes of these differences are not well understood.