Multiple eccrine poromas in the setting of total body irradiation and immunosuppression.

Eccrine poromas are benign, adnexal tumors that most often occur as a solitary lesion on the palm or sole. The occurrence of multiple eccrine poromas is extremely rare. In this report, we describe the development of several eccrine poromas in an acral distribution in a 42-year-old man.

Update in dermatopathology.

Inflammatory skin disease is a diagnostic challenge for both dermatologists and pathologists. Unlike the diagnosis of cutaneous neoplasms, biopsies of inflammatory disorders generally present a differential diagnosis for the pathologist. Similarly, the dermatologist is also presented with a clinical differential diagnosis prompting the biopsy.

Posttransplantation lymphoproliferative disease with features of lymphomatoid granulomatosis in a lung transplant patient.

A 58-year-old lung transplant patient developed worsening shortness of breath and indurated erythematous plaques on the lower left leg. A skin biopsy specimen revealed a dense angiocentric and angioinvasive infiltrate in the mid to reticular dermis and panniculus containing large, atypical lymphocytes with convoluted nuclei and prominent nucleoli. Immunohistochemical stains showed that the atypical cells were of B-cell origin, and that Epstein-Barr virus was present.