Publications by authors named "K S Conn"
Article Synopsis
- Psilocybin, a substance found in certain mushrooms, shows promise in helping people with depression by making them feel happier and less negative after treatment.
- Researchers studied how psilocybin affects rats in a game where they have to choose between two options for rewards, and found that the rats were more engaged and got more rewards after taking psilocybin.
- The study suggests that psilocybin might help people feel more optimistic by changing the way they process information, which could be helpful for those struggling with depression.
Article Synopsis
- * The study employs high-resolution imaging to reveal that the presence and positioning of histones at individual HSV-1 genomes show significant variability, impacting transcription regulation during the early stages of infection.
- * The host protein Daxx, along with PML factors, plays a crucial role in modifying histones to control viral genome decompaction, which is manipulated by the virus’s own proteins, highlighting a complex interplay between viral strategies and host responses during infection.
The gut microbial ecosystem communicates bidirectionally with the brain in what is known as the gut-microbiome-brain axis. Bidirectional signaling occurs through several pathways including signaling via the vagus nerve, circulation of microbial metabolites, and immune activation. Alterations in the gut microbiota are implicated in Alzheimer's disease (AD), a progressive neurodegenerative disease.
View Article and Find Full Text PDFThe resurgence of interest in psychedelics as treatments for psychiatric disorders necessitates a better understanding of potential sex differences in response to these substances. Sex as a biological variable (SABV) has been historically neglected in medical research, posing limits to our understanding of treatment efficacy. Human studies have provided insights into the efficacy of psychedelics across various diagnoses and aspects of cognition, yet sex-specific effects remain unclear, making it difficult to draw strong conclusions about sex-dependent differences in response to psychedelic treatments.
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