Publications by authors named "K S Choe"
Patients with gout have several coexisting conditions that impact mortality. We analyzed the differences in clinical manifestations among Korean patients with gout and compared the causes of death based on sex using data from the Korean National Health Insurance Service-National Sample Cohort database. We included adults with gout receiving urate-lowering therapy (ULT) from 2002 until 2019.
View Article and Find Full Text PDFObjective: This study aimed to evaluate the prognosis of root canal treatment (RCT) in dogs with complicated crown-root fractures (CCRFs) of the maxillary fourth premolar (PM4), focusing on the impact of periodontal probing depth (PPD) and furcation involvement on treatment outcomes.
Methods: The study analyzed 122 PM4 teeth affected by CCRF in dogs. The primary outcomes were the success rates of RCT, measured against PPD, and the degree of furcation involvement (stages F0, F1, and F2).
Background: Neurodegenerative disorders, including Alzheimer's disease (AD), have been linked to alterations in tryptophan (TRP) metabolism. However, no studies to date have systematically explored changes in the TRP pathway at both transcriptional and epigenetic levels. This study aimed to investigate transcriptomic, DNA methylomic (5mC) and hydroxymethylomic (5hmC) changes within genes involved in the TRP and nicotinamide adenine dinucleotide (NAD) pathways in AD, using three independent cohorts.
View Article and Find Full Text PDFBackground: Identifying patients with chest pain potentially due to acute coronary syndrome (ACS) early is crucial for triage nurses. They need a reliable, validated screening tool.
Aims: This study aims to develop an initial screening scale to detect ACS in patients presenting with chest pain in the emergency department.
Article Synopsis
- Alzheimer's disease is a brain condition that causes memory loss and other problems due to bad proteins, like amyloid beta plaques and tangles, building up in the brain.
- This study looked at how a vitamin E version called Trolox could help reduce these problems in mice that were given amyloid beta to mimic Alzheimer's.
- Results showed that Trolox helped the mice by lowering harmful proteins, reducing inflammation, and improving memory, which suggests it could be useful for finding new treatments for Alzheimer's disease.