Early antiviral CD4+ and CD8+ T cells are associated with upper airway clearance of SARS-CoV-2.

T cells are involved in protective immunity against numerous viral infections. Data regarding functional roles of human T cells in SARS-CoV-2 (SARS2) viral clearance in primary COVID-19 are limited. To address this knowledge gap, we assessed samples for associations between SARS2 upper respiratory tract viral RNA levels and early virus-specific adaptive immune responses for 95 unvaccinated clinical trial participants with acute primary COVID-19 aged 18-86 years old, approximately half of whom were considered at high risk for progression to severe COVID-19.

Role of macroalgal blue carbon ecosystems in climate change mitigation.

This review explicitly emphasizes the important yet unnoticed potential of macroalgae, such as seaweeds and kelps, as a powerful nature-based solution for climate change mitigation, with greater focus on the Indian Ocean seaweed diversity and efforts towards their conservation and management. Despite the IPCC's recognition of Blue Carbon ecosystems, seaweed ecosystems remain largely excluded from carbon accounting and policy frameworks. Herein, we specifically focus on the immense capacity of macroalgae globally and in the Indian Ocean coastal communities to sequester carbon, support marine biodiversity, and provide a range of ecosystem services.