Publications by authors named "K S Bisht"
In India, the Trans-Himalayan zone lies in the rain shadow of the main Himalayan region and is usually described as a "high-altitude cold desert". These regions are represented by sparse but unique vegetation composition. The present study is an attempt to investigate the vegetation composition in the alpine ecosystem of the cold desert landscape of the Nelang Valley in Western Himalayas (Uttarakhand), India.
View Article and Find Full Text PDFThe International Staging System for multiple myeloma recently underwent a second revision (R2-ISS) to include gain/amplification of 1q21 and account for the additive prognostic significance of multiple high-risk features. The phase 3 ICARIA-MM (isatuximab-pomalidomide-dexamethasone vs. pomalidomide-dexamethasone) and IKEMA (isatuximab-carfilzomib-dexamethasone vs.
View Article and Find Full Text PDFBackground: An eschar is not always present in all scrub typhus patients. Furthermore, such patients may present to tertiary care hospitals after administration of doxycycline. The present study aimed to determine the usefulness of using the swab from eschar sites in the diagnosis of scrub typhus in patients who present post-doxycycline therapy.
View Article and Find Full Text PDFArticle Synopsis
- Multiple myeloma (MM) is currently incurable, but natural killer (NK) cells show potential as a treatment option due to their role in targeting tumor cells.
- NK cells vary in their characteristics (like surface markers) and effectiveness, with certain subsets being linked to better patient outcomes, especially in relation to disease stages.
- Current MM treatments can influence NK cell behavior, suggesting that combining NK cell enhancements with existing therapies may improve overall treatment effectiveness.
Background: In the intricate landscape of healthcare amid the COVID-19 pandemic, the emergence of mucormycosis as a severe complication posed a significant challenge to primary healthcare. This study delved into the complexities of adverse drug reactions (ADRs) in COVID-19 patients with mucormycosis undergoing treatment with conventional amphotericin B.
Methods: Ethically approved and meticulously conducted, the study scrutinized 154 ADRs in depth, shedding light on their classification, outcomes, and interventions in COVID patients with mucormycosis.