Publications by authors named "K S Al-Khairy"
Article Synopsis
- The study investigates the use of cord blood for screening neonates for glucose-6-phosphate dehydrogenase (G6PD) deficiency compared to traditional peripheral blood samples, focusing on incidence and gender distribution.
- Analyzed data from over 8,000 neonates indicated a 2% incidence of G6PD deficiency, with a higher prevalence in males (79%) compared to females (21%), revealing significant gender differences (p < .001).
- Results showed no significant difference in identifying G6PD deficiency between cord and peripheral blood; however, cord blood had a high sensitivity of 98.6% and a negative predictive value of 99.5%, suggesting its reliable use for neonatal screening.
We explored the feasibility of collecting convalescent plasma for passive immunotherapy of Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using ELISA to screen serum samples from 443 potential plasma donors: 196 patients with suspected or laboratory-confirmed MERS-CoV infection, 230 healthcare workers, and 17 household contacts exposed to MERS-CoV. ELISA-reactive samples were further tested by indirect fluorescent antibody and microneutralization assays. Of the 443 tested samples, 12 (2.
View Article and Find Full Text PDFAs of September 30, 2015, a total of 1589 laboratory-confirmed cases of infection with the Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to the World Health Organization (WHO). At present there is no effective specific therapy against MERS-CoV. The use of convalescent plasma (CP) has been suggested as a potential therapy based on existing evidence from other viral infections.
View Article and Find Full Text PDFObjective: To evaluate the etiology of extremely elevated erythrocyte sedimentation rate (ESR) in adolescents and adults at a tertiary care center.
Methods: This retrospective, cross-sectional, observational study was carried out at King Abdulaziz Medical City, Riyadh, Saudi Arabia using the Westergren method of determining ESR in adolescents and adults aged >or=12 years. The patients included inpatients and outpatients with medical, surgical, and gynecological problems.
Background: The clinical features of acute myeloblastic leukemia (AML) and its response to therapy in adult patients in Saudi Arabia are not well defined, as only scanty data has been available. This situation will likely continue unless experience with AML is reported from different institutions in the Kingdom.
Patients And Methods: In this retrospective study, the records of 52 adult patients with previously untreated de novo acute myeloblastic leukemia (AML) who were treated at King Khalid University Hospital over a five-year period from January 1989 to December 1993 according to the conventional â3+7â regimen were reviewed.