Publications by authors named "K S A Myint"
Background: Cancer immune evasion is a multifaceted process that synchronizes pro-tumoral immune infiltration, immunosuppressive inflammation, and inhibitory immune checkpoint expression (IC). Current immunotherapies combat this issue by reinstating immunosurveillance of tumors; however, it benefits a limited patient population. Thus, a more effective immunotherapeutic strategy is warranted to cater to specific patient populations.
View Article and Find Full Text PDFA diarylheptanoid derivative mediates glycogen synthase kinase 3β to promote the porcine muscle satellite cell proliferation: Implications for cultured meat production.
Biochem Biophys Res Commun
December 2024
Skeletal muscle stem cells, or satellite cells, are vital for cultured meat production, driving proliferation and differentiation to form muscle fibers in vitro. However, these abilities are often compromised after long-term in vitro culturing due to a loss of their stemness characteristics. Therefore, effective pharmacological agents that enhance satellite cell proliferation and maintain stemness ability are needed for optimal cell growth for cultured meat production.
View Article and Find Full Text PDFBackground: The elevation of IQGAP3 expression in diverse cancers indicates a key role for IQGAP3 in carcinogenesis. Although IQGAP3 was established as a proliferating stomach stem cell factor and a regulator of the RAS-ERK pathway, how it drives cancer growth remains unclear.
Objective: We define the function of IQGAP3 in gastric cancer (GC) development and progression.
Article Synopsis
- Respiratory infections lead to millions of hospital visits globally and can be caused by various pathogens, including viruses, bacteria, and fungi.
- A study in Wattansoppeng, South Sulawesi, analyzed 210 respiratory specimens, finding positive cases for several viruses, including RSV-A, RSV-B, and different strains of human rhinovirus.
- The influenza virus identified was the seasonal H3N2 subtype, and the study highlighted that most affected individuals were children, though the severity of their infections was not clearly understood.
Importance: In Myanmar, amid political and civil unrest, droves of Burmese are displaced to neighboring countries including Thailand. Since the COVID-19 pandemic, little is known about the available healthcare services and health and well-being among refugees and migrant workers within resettlement areas along the Myanmar-Thailand border.
Objective: To explore the unmet needs of migrants along the Thailand-Myanmar border during the COVID-19 pandemic and their reasons for leaving Myanmar.