Publications by authors named "K S"

The Suzuki-Miyaura Coupling (SMC) reaction is a powerful method for forming carbon-carbon bonds in organic synthesis. Recent advancements in SMC reactions have introduced first-row transition metal catalysts, with zinc garnering significant interest due to its cost-effective and eco-friendly nature. Despite progress in experimental protocols, the mechanistic details of zinc-catalyzed SMC reactions are limited.

View Article and Find Full Text PDF
Article Synopsis
  • RbgA is a GTPase that plays a crucial role in the maturation of the 50S ribosomal subunit, favoring its GTP-bound state over the GDP-bound state due to conformational differences.
  • All-atom molecular dynamics simulations revealed significant conformational changes in RbgA depending on the bound nucleotide, particularly under GTP-Mg and GMPPNP-Mg conditions, which may impact its function.
  • The study identifies key regions that influence RbgA's ribosome association and suggests that understanding these mechanisms can help develop new chemical agents to regulate ribosome biogenesis.
View Article and Find Full Text PDF

Angiomyxomas, also known as vascular myxolipomas, are a rare type of soft tissue tumor characterized by the proliferation of adipose tissue within a myxoid stroma accompanied by multiple vascular channels. They represent a distinct variant of lipomas and require differentiation from other benign and malignant lipoma subtypes. Despite their rarity, only a few cases of angiomyxolipoma have been documented in medical literature.

View Article and Find Full Text PDF

Introduction: Heavy work in scorching temperatures can cause dehydration and heat stress, which can lead to a number of heat-related diseases. Heavy work in intense heat without rest or hydration is the main cause. The "Water, Rest, Shade" (WRS) intervention program for outdoor workers in hot weather reduces heat stress.

View Article and Find Full Text PDF

The technological advancement of Additive Manufacturing has enabled the fabrication of various customized artifacts and devices, which has prompted a huge demand for multimaterials that can cater to stringent mechanical, chemical, and other functional property requirements. Photocurable formulations that are widely used for Digital Light Processing (DLP)/Stereolithography (SLA) 3D printing applications are now expected to meet these new challenges of hard and soft or stretchable structural requirements in addition to good resolution in multiple scales. Here we present a biocompatible photocurable resin formulation with tunable mechanical properties that can produce hard or stretchable elastomeric 3D printed materials in a graded manner.

View Article and Find Full Text PDF