Human papillomavirus 6/11, 16 and 18 in oral carcinomas and benign oral lesions.

We have examined 118 oral squamous cell carcinomas, 72 oral leukoplakias, 12 cases of cheilitis and 65 of oral lichen planus for the presence of human papillomavirus (HPV) 6/11, 16 and 18 DNA by PCR/Southern blot hybridization. HPV DNA were found in 51/118 carcinomas (43.2%), in 16/72 (22.

[Oral Langerhans cell granulomatosis simulating necrotizing gingivostomatitis].

An unusual case of nonhealing necrotizing gingivostomatitis in a 66-year-old man is described. Microscopic examination of biopsy material showed an infiltrate of Langerhans cells. Merely oral lesions of Langerhans cell granulomatosis--especially in an old person--occur very seldom.

Human papillomavirus DNA in oral squamous cell carcinomas and normal mucosa.

Human papillomavirus (HPV) infections in oral carcinomas and normal oral mucosa were studied by consensus primer screening and typing for HPV types 6/11, 16 and 18 DNA. After polymerase chain reaction (PCR) the DNA species of interest were identified by Southern blot hybridization with digoxigenin-labeled oligonucleotide probes. Frozen tissue and scrapings were equally suitable for HPV testing and yielded high HPV detection rates in carcinomas.

[Necrotizing sialometaplasia].

The necrotising sialometaplasia is a rare disease of the orofacial system. The minor salivary glands of the palate are the main localisation. It's clinical importance consists in the possibility of confusion with squamous cell carcinoma or the mucoepidermoid tumor.

[The effect of chlorhexidine on the pulp-dentin system (research on the canine dental pulp)].

The effect on the pulp-dentin system by chlorhexidine 0.2% in comparison to the physiological sodium chloride solution was investigated in animal experiments. The methods of tests were based on the requirements of FDI 1980.