Publications by authors named "K Ruble"
Voicing My CHOiCES (VMC) is an advance care planning (ACP) guide designed to assist adolescents and young adults (AYAs) with serious illness in communicating their care preferences to others. This study evaluated a revised version of VMC. A structured interview was used alongside two versions of VMC to solicit AYA preferences and feedback regarding content and layout changes.
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- Youth with life-limiting conditions, like cancer, experience significant psychosocial challenges such as anxiety, depression, and pain, which can negatively impact long-term health outcomes.
- The study involved 100 English-speaking pediatric outpatients aged 8-21 who completed a brief distress screener called Checking IN, alongside caregiver-proxy reports, to assess their psychosocial distress.
- Results showed that both youth and caregivers identified fatigue, worry, and sleep difficulties as significant issues, highlighting the effectiveness of real-time assessments in improving psychosocial support and referral processes for distressed youth.
Background: Sleep problems following childhood cancer treatment may persist into adulthood, exacerbating cancer-related late effects and putting survivors at risk for poor physical and psychosocial functioning. This study examines sleep in long-term survivors and their siblings to identify risk factors and disease correlates.
Methods: Childhood cancer survivors (≥5 years from diagnosis; n = 12 340; 51.
Article Synopsis
- Centrosomes are crucial for organizing microtubules in cells, with sperm containing a specialized structure made up of different centrioles and pericentriolar material.
- Researchers studied the localization of centriole proteins CEP135 and CP110 in cattle and human sperm, both of which play roles in centriole structure and cilia formation.
- The antibodies used in the study identified CEP135 and CP110 near the expected locations in sperm centrioles, highlighting the unique functions of centrosomes in sperm development.
Article Synopsis
- The project aimed to improve support for childhood cancer survivors experiencing neurocognitive late effects by engaging parents, healthcare providers, and educators to identify research priorities regarding communication about these impacts.
- Using a combination of the SEED method and e-Delphi consensus approach, stakeholders participated in various engagement activities, resulting in the generation of 8 key research questions over the course of a year.
- The findings highlight the effectiveness of this collaborative process, offering a framework that can be applied to other healthcare challenges while addressing gaps in care for children facing neurocognitive issues.