Publications by authors named "K Rubin"
Background And Purpose: Major lower extremity amputation (MLEA) is associated with complications that may prolong length of hospital stay (LOS) and increase the risk of readmission. We primarily aimed to examine the LOS and risk of readmissions after MLEA in Denmark. Secondarily we investigated the time trends.
View Article and Find Full Text PDFBackground: Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by insulin resistance. A link has been suggested between insulin resistance and breast cancer, which is the most common cancer in women. Hence, women with previous GDM may be at increased risk of developing breast cancer, yet, the existing evidence is conflicting.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the effects of pertussis toxin (PTx) from Bordetella pertussis and its potential to induce autoimmune responses in mice, specifically examining its interaction with myelin oligodendrocyte peptide (MOG).
- Mice administered PTx and MOG didn't develop experimental autoimmune encephalomyelitis (EAE) but exhibited patchy alopecia in 36.4% of cases, linked to immune system changes around hair follicles.
- Histological analysis confirmed alopecia areata characteristics, showing a disruption of hair follicle immune privilege and increased immune cell activity, highlighting a potential connection between PTx exposure and immune system disorders.
Article Synopsis
- Concerns about falling (CaF) are widespread among older adults, particularly those with knee or hip osteoarthritis (OA), impacting their physical activity and social interactions.
- A study analyzed data from 7442 patients with OA, revealing that 48.1% had moderate CaF while 11.3% experienced high levels, with increased prevalence among older individuals and females.
- Pain, reduced physical function, and fear of movement were significantly linked to higher CaF, suggesting the need for integrating CaF assessments in OA management in primary care settings.
Background And Purpose: Mortality after major lower extremity amputations is high and may depend on amputation level. We aimed to examine the mortality risk in the first year after major lower extremity amputation divided into transtibial and transfemoral amputations.
Methods: This observational cohort study used data from the Danish Nationwide Health registers.