Publications by authors named "K Roe"

Article Synopsis
  • Hypoadrenocorticism in cats is rare, often presenting with abnormal serum sodium and potassium levels, but some cases show normal values; a study analyzed 41 cats with varying results.* -
  • The study found that cats with electrolyte imbalances were more likely to exhibit symptoms like hypothermia and weakness, while over half of the subjects (85.4%) were discharged after treatment.* -
  • About one-third of the cats showed hypercalcemia, and those without serious underlying conditions often had a good prognosis post-hospitalization; testing for exocrine pancreatic insufficiency is recommended.*
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Lethal synergistic infections by concurrent pathogens have occurred in humans, including human immunodeficiency virus and Mycobacterium tuberculosis infections, or in animal or human models of influenza virus, or bacteria, e.g., Streptococcus pneumoniae, concurrent with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

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Emerging studies have highlighted the importance of tissue-resident B cells in the lungs, for protective immunity against respiratory viruses. However, the mechanisms controlling generation and maintenance of such tissue-resident B cells at respiratory sites remain obscure. We have previously shown that αv integrins limit B cell responses to antigens containing Toll-like receptor ligands, and that deletion of B cell αv integrins, in mice, enhances germinal center (GC)-derived long-lived B cell responses after systemic immunization with viral antigens.

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Background: Post-traumatic stress disorder (PTSD) is highly prevalent in veterans and associated with impairments in family functioning, including parenting. There is a bidirectional relationship between PTSD and familial functioning such that impaired functioning is related to increases in trauma-related symptoms, and vice versa. Despite this known bidirectional association, there is currently no trauma-informed parenting intervention available for veterans within the Department of Veterans Affairs (VA).

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Article Synopsis
  • A 56-year-old transgender woman with HIV presented to the emergency department due to visual disturbances and bilateral papilledema, but initial imaging did not show any intracranial issues.
  • A lumbar puncture revealed syphilis in her cerebrospinal fluid, leading to a diagnosis of bilateral syphilitic uveitis, and she was treated successfully with penicillin.
  • This case highlights the need for early syphilis screening in transgender individuals with HIV who have visual symptoms and emphasizes the healthcare barriers they face, which can delay treatment and increase the risk of serious complications.
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