Publications by authors named "K Ri"

Article Synopsis
  • The GM(1,1) model is popular for its low sample and computational requirements but often struggles with prediction accuracy despite good fitting results.
  • This paper introduces an enhanced GM(1,1) model, called OB-WMSE-GM(1,1), which focuses on improving predictive accuracy through a weighted mean squared error approach.
  • The new model outperformed traditional GM(1,1) models in various tests, achieving lower error metrics in simulations and real-world applications, and can further improve when combined with other techniques.
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Ischemic retinopathies including diabetic retinopathy are major causes of vision loss. Inner blood-retinal barrier (BRB) breakdown with retinal vascular hyperpermeability results in macular edema. Although dysfunction of the neurovascular unit including neurons, glia, and vascular cells is now understood to underlie this process, there is a need for fuller elucidation of the underlying events in BRB dysfunction in ischemic disease, including a systematic analysis of myeloid cells and exploration of cellular cross-talk.

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Article Synopsis
  • Mutant EGFR is a key driver in non-small cell lung cancer (NSCLC), and while EGFR tyrosine kinase inhibitors (TKIs) like osimertinib are effective initially, most patients experience disease progression within 10-19 months due to drug-tolerant cells.
  • Research shows that while osimertinib partially inhibits EGFR activation, tumor cells can reactivate survival signaling pathways, leading to regrowth after about 35 days of treatment.
  • The combination of osimertinib with an antibody against hepatoma-derived growth factor (HDGF) resulted in better tumor responses and prolonged survival in mice, suggesting that targeting HDGF might improve NSCLC treatment outcomes.*
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Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and FLVCR2) are members of the major facilitator superfamily. Their dysfunction is linked to several clinical disorders, including PCARP, HSAN and Fowler syndrome. Earlier studies concluded that FLVCR1 may function as a haem exporter, whereas FLVCR2 was suggested to act as a haem importer, yet conclusive biochemical and detailed molecular evidence remained elusive for the function of both transporters.

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Raising the speed and accuracy of displacement retrieval by overcoming the weakness of time-consuming parameter estimation and a complex displacement retrieval algorithm is of key importance in improving the real-time quality of optical feedback self-mixing-based displacement measurement sensor. This paper proposes a high-speed and accurate simultaneous estimation method of displacement, optical feedback factor, and linewidth enhancement factor based on data fitting near a half-fringe cooperating with the fringe-counting method. The displacement measurement accuracy of the proposed method is about 16 nm.

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