Background: miRNAs are non-coding RNA that are recognized as biomarkers of kidney disorders. There is limited information on the differential expression of miRNA and their target genes in idiopathic nephrotic syndrome of childhood.
Methods: We enrolled patients, 2-18 years old, with steroid-sensitive nephrotic syndrome, either at onset or during relapse, and steroid-resistant disease, at diagnosis of steroid-resistance.
The reduction of abundant benzene rings to scarce C(sp)-rich motifs is invaluable for drug design, as C(sp) content is known to correlate with clinical success. Cyclohexenes are attractive targets, as they can be rapidly elaborated into large product libraries and are stable against rearomatization. However, partial reduction reactions of benzenes to cyclohexenes are rare and have a very narrow scope.
View Article and Find Full Text PDFAir pollution in the interior of our homes is caused by diverse chemical, physical, and biological entities. This review comprehensively explores the current understanding of sources and health impacts of gaseous and particulate pollutants. Trend analysis of indoor air research worldwide revealed a quantum jump of 2.
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