Publications by authors named "K Reisinger"
Article Synopsis
- Ankle fracture-dislocations can sometimes require delayed internal fixation, and a study aimed to compare immediate surgical intervention (ORIF) with delayed methods using external fixation or cast splints.
- The study included 447 patients from various hospitals in the Netherlands and found that surgery within 48 hours did not significantly affect unscheduled re-operation rates or surgical site infection (SSI) when compared to delayed options.
- Factors like higher body mass index (BMI) and open fractures increased the likelihood of re-operation, while diabetes and open fractures were linked to higher SSI rates, suggesting that prompt surgery is safe when soft tissue conditions permit it.
Operative management of rib fractures has gained significant popularity over the last years, however, it remains a controversial topic, due to the substantial heterogeneity among rib fracture patients with considerable differences in epidemiology. Hence, the present narrative review aims to provide an overview of the treatment and (long-term) outcomes of rib fractures, with an emphasis on the surgical treatment. Nowadays, computed tomography (CT) has been shown to be most practical and sensitive for detecting rib fractures, of which up to 50% is missed on other imaging modalities.
View Article and Find Full Text PDFBackground: The Trans Rectus Sheath Extra-Peritoneal Procedure (TREPP) is an open procedure in which the mesh is placed in the preperitoneal space and is therefore associated with less chronic post-operative inguinal pain. TREPP is primarily performed under general or spinal anesthesia, however, it is also possible to perform under sedation and local anesthesia with potentially advantages. This retrospective feasibility pilot study investigates the safety and efficiency of TREPP under local anesthesia in the outpatient clinic in comparison with Lichtenstein.
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- - The comet assay is a flexible method used to identify DNA damage in individual eukaryotic cells, applicable to various species from yeast to humans, detecting issues like DNA strand breaks and other forms of damage.
- - Modifications to the protocol are necessary based on the specimen to minimize additional DNA damage during sample processing and to enhance the detection of damage differences.
- - The method has been validated for various applications in research and has gained recognition as an in vivo genotoxicity test by the OECD, with guidelines provided for its use across different cell types and DNA damage assessments.
The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the disparity between developed and developing countries for infectious disease surveillance and the sequencing of pathogen genomes. The majority of SARS-CoV-2 sequences published are from Europe, North America, and Asia. Between April 2020 and January 2022, 795 SARS-CoV-2-positive nares swabs from individuals in the U.
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