Publications by authors named "K Rawlik"
L. is a widespread liana that significantly influences forest ecosystems in temperate zones, exhibiting high adaptability to varying soil moisture and light levels. In this study, it was confirmed that dominates the herbaceous layer of the Kórnik Arboretum (Poland), with clear links between its above-ground biomass and key environmental factors.
View Article and Find Full Text PDFDespite extensive global research into genetic predisposition for severe COVID-19, knowledge on the role of rare host genetic variants and their relation to other risk factors remains limited. Here, 52 genes with prior etiological evidence were sequenced in 1,772 severe COVID-19 cases and 5,347 population-based controls from Spain/Italy. Rare deleterious TLR7 variants were present in 2.
View Article and Find Full Text PDFArticle Synopsis
- The FarmGTEx project aims to create a public database of genetic variants in livestock to connect genetic differences with physical traits, benefiting both animal breeding and human health research.
- The pilot phase, PigGTEx, involved analyzing 5,457 RNA-sequencing and 1,602 whole-genome sequencing samples from pigs, leading to the development of a genotype imputation panel and associations between millions of genetic variants and transcriptomic traits across 34 different tissues.
- The study highlights the tissue-specific regulatory effects of these variants, revealing molecular mechanisms affecting 207 complex pig traits while also demonstrating the relevance of pigs as models for understanding human gene expression and genetic regulation.
Article Synopsis
- Researchers analyzed genetic data from 24,202 critically ill COVID-19 cases, showing that host genetics can help identify effective immunomodulatory therapies.
- They conducted a meta-analysis that revealed 49 significant genetic associations, including 16 new ones not previously reported.
- Key findings include potential drug targets related to inflammation, immune response, and viral entry, which could lead to new treatment strategies for severe COVID-19 cases.