Publications by authors named "K Randolph"

Article Synopsis
  • * A pilot study involving 13 adults with PASC symptoms explored the impact of 9 months of daily growth hormone (GH) injections on various health measures and self-reported outcomes, such as fatigue and quality of life.
  • * Results showed significant improvement in fatigue and mood-related scores, but no significant changes were observed in cognition, body composition, physical performance, or GH secretion levels after treatment.
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Introduction: Cognitive impairment is reported in a variety of clinical conditions including Alzheimer's disease, Parkinson's and 'long-COVID'. Interestingly, many of these clinical conditions are also associated with microbial dysbiosis. This comanifestation of cognitive and microbiome findings in seemingly unrelated maladies suggests that they could share a common mechanism and potentially presents a treatment target.

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Article Synopsis
  • The study aimed to identify issues related to the safe handling and disposal of chemotherapy agents in low and middle-income countries, focusing on Nigeria.
  • Two surveys were conducted: one assessing the needs of health professionals in 2019 and another evaluating a chemotherapy facility's compliance with safety standards in 2021.
  • Results revealed significant gaps in training and satisfaction with current practices, indicating a pressing need for improved resources and strategies to ensure safe chemotherapy administration.
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Introduction: Patients who suffer a traumatic brain injury (TBI) often experience chronic and sometimes debilitating sequelae. Recent reports have illustrated both acute and long-term dysbiosis of the gastrointestinal microbiome with significant alterations in composition and predicted functional consequences.

Methods: Working with participants from past research, metagenomic stability of the TBI- associated fecal microbiome (FMB) was evaluated by custom qPCR array comparing a fecal sample from 2015 to one collected in 2020.

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Background: Following traumatic brain injury (TBI) some patients develop lingering comorbid symptoms of fatigue and cognitive impairment. The mild cognitive impairment self-reported by patients is often not detected with neurocognitive tests making it difficult to determine how common and severe these symptoms are in individuals with a history of TBI. This study was conducted to determine the relative prevalence of fatigue and cognitive impairment in individuals with a history of TBI.

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