Publications by authors named "K Rakhimov"

Background: At present, more than 8000 sesquiterpene lactones have been isolated and described from natural sources, a significant part of which has cytotoxicity and antitumor activity. One of the practically available sesquiterpene lactones is arglabin, which, as a renewable material, is used for the synthesis of new compounds. The article presents data on the study of cytotoxicity and antitumor activity of the arglabin and its derivatives using molecular modeling methods and, in the experiment and .

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Species of the genus Artemisia are well known for their use as ingredients in ancient medicine. The advantage of using plant extracts compared to individual pharmaceutical ingredients is the rate of adaptation of the pathogenic microorganisms to the drug. Due to the rapid development of multidrug-resistance in microorganisms in the field, it is essential to search for novel, effective drugs with low toxicity.

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The use of medicinal plants has increased significantly in recent years. More than 80% of the world's population uses medicinal plants to treat themselves. Many antibacterial and anti-inflammatory synthetic drugs are available in medical practice.

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Article Synopsis
  • Crimean-Congo hemorrhagic fever (CCHF) is a serious disease found in Kazakhstan, with a previously estimated 1.2% infection rate among livestock owners in certain regions.
  • A study tested for the presence of CCHF virus in 521 sheep and 454 cattle across various villages, revealing seroprevalence rates of 5.7% in sheep and 22.5% in cattle, indicating higher risk in endemic areas.
  • The findings suggest that the areas previously identified as nonendemic still pose a risk for CCHF transmission, highlighting the need for enhanced public health measures even in these regions.
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