Publications by authors named "K Rak"
Just as overweight and obesity may impair immunity, excessive body weight-related parameters of women in the pre-conception period and during pregnancy are possible detrimental factors for fetal programming of the immune system in their offspring. We investigated the relationship of pre-pregnancy body mass index (pBMI) and gestational weight gain (GWG) of mothers with the placental transport rate (PTR) of IgG antibodies and antineutrophil cytoplasmatic antibodies against lactoferrin (Lf-ANCA) and their concentration in umbilical cord blood serum (UCS), verifying the sex-specificity of this relationship. The examined group of this cross-sectional pilot study consisted of 101 pregnant women and their healthy CS-delivered newborn children.
View Article and Find Full Text PDFBackground: Precise preoperative radiological evaluation of aural atresia is of utmost importance for surgical planning. Until now, multislice computed tomography (MSCT) has been used but it cannot adequately visualize small structures such as the stapes. Flat-panel volume CT (fpVCT) with its secondary reconstructions (fpVCT) offers a high-resolution visualization of the middle ear.
View Article and Find Full Text PDFInactivity of Stat3 in sensory and non-sensory cells of the mature cochlea.
Front Mol Neurosci
October 2024
Signal transducer and activator of transcription 3 (Stat3) plays a role in various cellular processes such as differentiation, inflammation, cell survival and microtubule dynamics, depending on the cell type and the activated signaling pathway. Stat3 is highly expressed in the hair cells and supporting cells of the cochlea and is essential for the differentiation of mouse hair cells in the early embryonic stage. However, it is unclear how Stat3 contributes to the correct function of cells in the organ of Corti postnatally.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on how otolaryngologists approach testing for congenital sensorineural hearing loss, specifically looking at cCMV infection and genetic testing methods.
- A survey of 20 otolaryngologists showed that 90% use cCMV and genetic tests, with 95% applying cCMV testing in their practices, and many pursue broader genetic screening if initial tests return negative.
- The findings also highlight reimbursement rates for these tests, revealing that a majority of respondents receive coverage for cCMV, genetic variant testing, and wider genetic screening.
Background: The association of sarcopenia and frailty syndrome with dietary patterns is not yet well recognized.
The Aim: The aim of the study was to evaluate the association among dietary patterns, suspected sarcopenia, and frailty syndrome among older people in Poland.
Methods: The study was conducted in 2022 and 2023 among people aged 55 and older.