Publications by authors named "K R Talaat"

Coinfection with human papillomavirus (HPV) and HIV compounds the risks of developing cervical, anal, and HPV-associated oral neoplasia. Safe prophylactic vaccines are available to prevent HPV infections in people with HIV(PWH). Yet, vaccine efficacy and duration of protection remain questionable.

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Importance: Limited randomized clinical trial data exist on the safety of simultaneous administration of COVID-19 and influenza vaccines.

Objective: To compare the reactogenicity, safety, and changes in health-related quality of life (HRQOL) after simultaneous vs sequential receipt of messenger RNA (mRNA) COVID-19 vaccine and quadrivalent inactivated influenza vaccine (IIV4).

Design, Setting, And Participants: This randomized, placebo-controlled clinical trial was conducted between October 8, 2021, and June 14, 2023, at 3 US sites.

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Importance: Quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) and adjuvanted recombinant zoster vaccine (RZV) contain novel adjuvants. Data are limited on the comparative safety, reactogenicity, and health-related quality of life (HRQOL) effects of the simultaneous administration of these vaccines.

Objective: To compare the safety and reactogenicity after simultaneous doses of RZV and aIIV4 administration (opposite arms) with simultaneous doses of RZV with quadrivalent high-dose inactivated influenza vaccine [HD-IIV4]).

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Article Synopsis
  • Anbar province, specifically Hadeetha, experienced significant health care disruptions during the conflicts from the U.S. invasion in 2003 and ISIS occupation from 2014-2017, leading to changes in health-seeking behaviors among caregivers of young children.
  • The mixed-methods study conducted from 2019 to 2021 involved a household survey of 415 caregivers and focus groups with healthcare workers to understand shifts in healthcare access and practices post-conflict.
  • Findings revealed that post-conflict, 79% of caregivers sought care from physicians compared to just 47% during the conflict, while healthcare workers identified major challenges in service delivery during the ISIS years due to infrastructure damage and threats to safety.
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The SARS-COV2 pandemic caused significant disruptions in immunization delivery. Baseline deficit gaps in immunization completion exacerbated ongoing disparities in immunization coverage in low- and middle-income. Emerging reports focused on global strategies for return to routine immunization schedules.

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