Publications by authors named "K R Sugumaran"

Background In gallbladder cancer (GBC), extrahepatic bile duct (EHBD) resection is selectively performed if gross direct extension or microscopic involvement of the cystic duct margin (CDM) is detected. Although CDM is usually sent for frozen biopsy intraoperatively in most centers, there are no studies regarding the routine use of CDM frozen biopsy irrespective of the tumor location and paucity of literature regarding the impact of CDM status on recurrence-free and overall survival in GBC. The presence of obstructive jaundice in GBC usually indicates the involvement of EHBD or cystic duct-bile duct junction.

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Objectives: Patients with stage IV gallbladder cancer (GBC) have a dismal prognosis. Mostly, they are not amenable to surgical treatment. However, in some of them, a potentially curative surgical resection is possible.

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Article Synopsis
  • The study investigates histopathological changes in the liver associated with chronic pancreatitis (CP), focusing on incidence, risk factors, and long-term outcomes.
  • Among 73 CP patients analyzed, the majority were young males, with varying liver conditions categorized as normal, fatty liver, or inflammation/fibrosis.
  • Results indicate that patients with liver inflammation or fibrosis had higher mortality rates, emphasizing the need for careful monitoring of these patients for potential complications.
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Hydatid disease is a zoonotic disease, mainly prevalent in endemic countries. The liver and lungs are the most commonly affected organs in hydatid disease. Primary hydatid cyst of the pancreas is rare, and pancreatitis due to hydatid cyst has rarely been listed in the literature.

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Lettuce (Lactuca sativa) is grown in various parts of the world for use as a leafy vegetable. Although the use of light-emitting diode (LED) in controlled plant production systems has been successfully used to enhance nutritional quality and plant growth efficiently, the molecular basis of lettuce's response to varying light spectra is not studied. Using next-generation sequencing, we have analyzed the transcriptomes of leaf lettuce (Lactuca sativa var.

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