Nano selenium modulates ripening of Capsicum fruit under postharvest storage: Cellular redox and related physiological characteristics.

In the background of antioxidation properties of selenium (Se) in plants, the role of nano‑selenium (Se-NPs) was justified in the modulation of Capsicum fruit ripening. In our study, exogenous application of 8 mg L Se-NPs on fruits through 7 days (D) of postharvest storage regulated decay rate, water loss and fruit coat firmness. Se-NPs recovered fruit coat damages with reduction of ion leakage, lipid oxidation, and accumulation of polyamines.

Investigating the association of VHL gene variants with disease risk and clinicopathological outcomes in ccRCC patients from West Bengal, India.

Background: Clear cell renal cell carcinoma (ccRCC) is a prevalent and aggressive malignancy, with the von Hippel-Lindau (VHL) gene playing a critical role in its pathogenesis. However, the association between VHL gene variants and sporadic ccRCC risk remains unexplored in the Indian population. This study aimed to investigate the somatic and germline variants of the VHL gene in sporadic ccRCC patients from West Bengal, India, and their association with disease risk and clinicopathological parameters.

Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol.

Salmonella enterica serotype Typhimurium (Salmonella) resides and multiplies intracellularly in cholesterol-rich compartments called Salmonella-containing vacuoles (SCVs) with actin-rich tubular extensions known as Salmonella-induced filaments (SIFs). SCV maturation depends on host-derived cholesterol, but the transport mechanism of low-density lipoprotein (LDL)-derived cholesterol to SCVs remains unclear. Here we find that peroxisomes are recruited to SCVs and function as pro-bacterial organelle.

Exploring the Potential Fungicidal Applications of a Cu(II) Complex with Schiff Base and Carboxylates against .

Given the critical need to preserve agricultural sustainability, there is an urgent call to address fungal infections. Our study presents a promising approach by focusing on SIX (Secreted in Xylem) proteins as a pivotal target for the development of innovative fungicidal strategies. Within the sphere of this study, we meticulously scrutinize the antifungal efficacy of our synthesized Cu(II) complex formulated as [Cu(L1)(L2)](ClO), where L1 represents ()-cyclohexyl-(pyridine-2-xlmethylene) methanamine and L2H denotes cinnamic acid, compared against a commercially available fungicide comprising 4% hexaconazole and 68% zineb.

An Epidemiological Study on Magnitude of Selected Components of Metabolic Syndrome and Its Risk Factors among First-year MBBS Students.

Background: Previous research has suggested that the prevalence of risk factors for cardiometabolic diseases is higher in South Asians, with premature presentation common in this subpopulation.

Aim: To explore this further, we assessed the prevalence of metabolic syndrome (MetS) components and risk factors among young adults.

Methods: This was a cross-sectional, epidemiological, institution-based study conducted at the Medical College in Eastern India.