Fibrous Dysplasia With Atypical Bilateral Upper Extremity Pattern.

Fibrous dysplasia (FD) typically presents unilaterally in the lower limbs, or in the skull, mandible, or pelvis. Bilateral presentation is rarely reported. Most cases are diagnosed in the teens with 75% of patients diagnosed before the age of 30 years.

Methotrexate & rheumatoid arthritis associated atherosclerosis: A narrative review of multidisciplinary approach for risk modification by the international board of experts.

Rheumatoid arthritis (RA) is an idiopathic, autoimmune connective tissue disorder that primarily affects the synovial joints, causing symmetric, erosive-deforming polyarthritis. It is also associated with extra-articular manifestations, particularly cardiovascular (CV) diseases (CVD). CV risk modification in RA remains unsolved despite recent advances in the management of RA.

Waist-To-Hip Ratio Predicts Abnormal Overnight Oximetry in Men Independent of Body Mass Index.

Ambulatory overnight oximetry (OXI) has emerged as a cost-effective initial test for sleep disordered breathing. Obesity is closely associated with obstructive sleep apnea (OSA); however, whether body mass index (BMI) or waist-to-hip ratio (WHR) predicts abnormal overnight OXI remains unknown. We performed a retrospective cross-sectional study of 393 men seen in the Executive Health Program at Mayo Clinic in Rochester, Minnesota who underwent ambulatory overnight OXI ordered by preventive medicine physicians between January 1, 2004 through December 31, 2010.

THE MOLECULAR MECHANISM OF DIABETES MELLITUS - RELATED IMPAIRMENT OF CARDIOVASCULAR HOMEOSTASIS (REVIEW).

Today, diabetes mellitus is an urgent and topical medical and social problem of modern medicine. In the era of industrialization, this endocrine disorder's incidence increases exponentially, affecting more broadly, especially the young cohorts of the population, thereby exerting a substantial burden on the health system. Comprehension and full-fledged study of the pathophysiological mechanisms and remodeling dynamics in the diabetic continuum will ensure further advances in modern diabetology to set it to a potentially new level.