Publications by authors named "K R Leander"

To investigate whether coronary artery disease (CAD) burden is associated with plasma levels of the myocardial biomarkers Troponin I (TropI) and NT-proBNP in a large population-based sample using a cross-sectional design. Coronary computerized tomography (CT) angiography was performed in 25,859 subjects without a history of atherosclerotic disease from SCAPIS study (age 50-65, 52% women). TropI and NT-proBNP were measured in plasma.

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  • This study investigated the relationship between transportation noise and atrial fibrillation (AF) using data from 11 Nordic cohorts, totaling over 161,000 participants.
  • Researchers found that higher road traffic noise exposure is linked to an increased risk of developing AF, particularly in women and overweight individuals.
  • Aircraft noise also showed a potential association with AF risk, while railway noise did not appear to be related; overall, road and aircraft noise combined raised the risk significantly.
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Background: Menopausal vasomotor symptoms (VMS) are increasingly emphasized as a potentially important cardiovascular risk factor, but their role is still unclear. We assessed the association between VMS and subclinical atherosclerotic cardiovascular disease in peri- and postmenopausal women.

Methods And Results: Using a cross-sectional study design, questionnaire data were collected from a population-based sample of women aged 50 to 64.

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  • The study aimed to explore sex differences in the prevalence of imaging-detected atherosclerosis in men and women, revealing that men are more likely to experience cardiovascular issues such as myocardial infarction.
  • Participants aged 50-65 from the SCAPIS study underwent advanced imaging, finding significantly higher rates of coronary and carotid atherosclerosis in men compared to women (e.g., 56.2% vs. 29.5% for coronary atherosclerosis).
  • Even after adjusting for factors like hypertension and diabetes, these sex differences in atherosclerosis prevalence persisted, indicating a greater cardiovascular risk for men, with older women showing comparable rates to younger men.
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